Facilities

OKAY Diagnostic Research Center provides facilities for upper and lower gastrointestinal endoscopy in its endoscopy laboratory.

Done by expert hands, Okay has acquired faith and confidence of the masses in procedures like oesophagoscopy, gastroscopy, duodenoscopy, foreign body removal from upper GI tract, balloon dilatation of oesophageal strictures and achalasia, biopsy, variceal banding, sclerotherapy etc. Sigmoidoscopy and colonoscopy have recently been introduced. Efforts are on for making a dedicated endoscopy laboratory where invasive procedures for hepatobiliary disease could be dealt with expertly.

Electroencephalography (EEG) at OKAY Diagnostic Research Center is computerised for acquiring brain wave patterns and removing artefacts. It provides rapid and convenient way to obtain EEG tracings and storing data.

Brain mapping facility is available which helps in localizing the abnormal EEG focus.

NIHON - KOHDEN

At OKAY Diagnostic Research Center, a computerised equipment performs pulmonary function tests entailing all lung parameters.

PFT provides useful information when compared after administration of bronchodilators. Early diagnosis of obstructive and restrictive lung disease is easily possible with the use of spirometry.

Conventional ECG is done on adults and infant in out laboratory besides home/bedside ECG facility. The multichannel, auto-reporting ECG machines are available.

Computerised Treadmill Exercise Testing is an invaluable tool for the early diagnosis of Ischemic Heart Disease. Further, this test has been incorporated in the general heath checkup of an individual after the age of 40 years.

The value of equipment lies in its accuracy to ascertain changes in the waveform of the continuous exercise. At OKAY Diagnostic Research Center, GE T2100 equipment is sensitive in determining these waveforms with reliable accuracy. The software is up-to-date and precisely calculates the variations brought about by exercise.

The output is presented on non-thermal paper so that it does not fade away with time.

OKAY Diagnostic Research Center was the first in Rajasthan to install Orthopantomogram (OPG) in 1987.

By the help of this machine, all the teeth are visualized on a single X-ray plate extra-orally. There is no need to put a X-Ray dental film inside the mouth. This is particularly helpful in those patients who cannot open their mouths. Its use is immense in cosmetic plastic and dental surgery, orthodontistry, oncosurgery and trauma.

Cephalogram can also be done with this machine. Temporomandibular joints can be best visualised with OPG machine.

Okay acquired latest digital radiography system from shimadzu. It saves 60% of time as there is faster registering of the patient and cassette is least handled. The image of the X-ray can be viewed immediately on the monitor after exposure.

The table top is moving so the patient need not be shifted for exposure. The bucky table can support patient weight upto 250kg.

OKAY Diagnostic Research Center was amongst the first to acquire the high end sonography machines in Rajasthan.

Apart from the usual sonography, the medical faculty is fully trained for conducting specialised procedures like transvaginal, transrectal, small parts, biopsy procedure sonography.

The image output facility has been enhanced by the introduction of “Laser Camera” which gives sharper and clearer images as compared to conventional multiformat camera images.

OKAY Diagnostic Research Center has installed a modern GE Logiq 500 equipment which is a high end machine for performing dynamic cardiac and vascular studies. “Power doppler” facility is also present in this machine which enables one to visualise smaller sized vesels especially useful in looking at renal and foetal cerebral vasculature.

The person behind the machine is a fully trained cardiologist with vast experience in the field. Computer networking enables him to obtain views and opinions of fellow experts online. Image storing facility is helpful to the patients for evolution of their functional cardiac status.

High frequency probe enables to do peripheral vascular doppler examination with precision in detecting obliterative plaque / thrombus.

For Osteoporosis management, OKAY Diagnostic Research Centre ushers in Bone Densitometry Solutions form GE-USA. Osteoporosis is a silent, progressive disease characterized by decreased bone density and increased bone fragility. The disease may progress silently for decades with no symptoms unit fractures occur. Women are at the greatest risk.

Bone loss in the major risk factor that can be modified in mid-life to reduce fracture risk. Bone loss can be reduced by treatment but it is difficult to restore the microarchitecture of the skeleton once bone has been lost. Early detection and intervention are crucial.

Here comes the utility of Bone Densitometry which assists physicians in diagnosis, fracture risk assessment end monitoring response to therapy.

Mammography

As a key contribution to women health, OKAY Diagnostic Research Center provides a state-of-art dedicated GE Mammography system capable of identifying small soft tissue pathologies of breast. It provides high resolution with magnification and better contrast facility at short exposure time.

The modern equipment exposes the patient to a lower X Ray radiation (0.25 Rads for 2 view bilateral mammography) than conventional X-Ray units which entail a radiation of about 3.2 Rads or more.

The screening guidelines by the American Cancer Society emphasise mammography for all women between the ages of 40-49 years once in two years and once in a year for those above 50 years of age. Early diagnosis is the crux for the successful management of Breast cancers and doctors can do invaluable service to post-menopausal women by advising them mammography.

In the eventuality of finding a pathological lesion, sonography of the breast is done free of cost to ensure a definitive diagnosis. Facility for a sono-guided biopsy is also available.

A lady technician is always available for conducting this investigatin.

COLOUR DOPPLER 2D ECHOCARDIOGRAPHY

OKAY Diagnostic Research Center has installed a modern GE Logiq 500 equipment which is a high end machine for performing dynamic cardiac and vascular studies. “Power doppler” facility is also present in this machine which enables one to visualise smaller sized vesels especially useful in looking at renal and foetal cerebral vasculature.

The person behind the machine is a fully trained cardiologist with vast experience in the field. Computer networking enables him to obtain views and opinions of fellow experts online. Image storing facility is helpful to the patients for evolution of their functional cardiac status.

High frequency probe enables to do peripheral vascular doppler examination with precision in detecting obliterative plaque / thrombus.

X-Ray has been an age old diagnostic procedure. The addition of an image intensifier (IITV) has revolutionised X-Ray radiology. In recent times, the images obtained by X-Ray machine have also been digitized.

When X-Rays modality is utilised for real time diagnostic purposes like myelography, bronchography, barium studies, urethrogram, fistulogram, hysterosalpingography (HSG), sonogram, T-tube cholangiography, PTC., the use of IITV is extraordinary. The X-Ray exposure is significantly redued to the patient and also to the radiologist doing the procedure.

At OKAY Diagnostic Research Center, IITV equipment (Siemens) was installed in the year 1987. Over all these years, the faculty has gathered enormous experience in conducting various procedures.

• 1.5T Light speed GE
• 1.5T Avanto Siemens
• 3.0T Achieva Phillips
• 3.0T Ingenia Phillips

MR imaging has ushered sea change in medical diagnosis due to its extensive clinical use. The latest acquisition of 3T ingenia from Phillips gives us high quality images. It has 70cm bore and has more space which reduces patient anxiety.
The scans are faster.

In head there is advanced neuro imaging package, motion free brain imaging, SWI for traumatic brain injury and advanced diffusion sequences. ASL – non contrast brain perfusion imaging will now be possible. High quality functional MRI will be performed.

Fat quantification in liver will be performed mDIXON technique. Healthy liver has about 5-6% fat content. Fatty liver is seen in those patients with excessive alcohol consumption, non alcoholic fatty liver disease (NAFLD). The patient NAFLD are at risk of developing cirrhosis and liver failure. Ultrasound has 70% sensitivity in detecting fat in liver (much less in obies patient). Liver biopsy while accurate is invasive with risk of complications. mDIXON provides high quality way of quantification fat in liver.

In cardiac imaging – myocardial viability studies and myocardial perfusion studies can be performed.

Breast MRI – it is most sensitive test to detect early breast cancer in women at high risk. Those women having strong family history of breast cancer should undergo this examination. Dense breast is better evaluated by MRI. In breast implant MRI is method of choice. In pre operative staging MRI is the accurate way of determining size and extent of breast carcinoma. Evaluation of response of cancer to drug treatment is better evaluated by MRI. After surgery residual tumor can be assessed by MRI.

Oncology imaging – whole body examination are possible due to rapid scans. DWIBS is used for reduction of metastases and lymphnode enlargement.

MR neurography - allows clear visualization of peripheral nerves.

OKAY has acquired Dual source CT (128 slice) with promises improvement in speed and coverage along with new clinical advances and applications. It uses two x-ray sources simultaneously.

Clinical benefits:

Imaging of all heart rates without beta blocker, scanning of arrhythmic patients, high accuracy of in-stent imaging. Acquisition is shortest breath hold.

One stop diagnostic modality for chest pain. Diagnosis of coronary artery disease, dissection of aorta and pulmonary thromboembolism can be made in single examination.

Direct subtraction of bone with dual energy application – useful in cases of angiography.

Virtual unenhanced liver image.

Evaluation of lung perfusion defects.

Visualization of cartilage, tendon and ligaments.

Kidney stone characterization.

Metallic artifact reduction.

Reduction in radiation dosage

OKAY Laboratory has started IHC testing for ER,PR,Her 2 Neu markers also apart from Biopsy processing and FNA reporting from efficient doctors.

Lieca Microtome

Biogenex Antigen Retrieval System

OKAY Laboratory has installed Biomerieux BactAlert 3D system and Vitek-2T for automation in microbiology lab.ChorusTRIO automated ELISA reader and Biomerieux Minividas for hepatitis marker studies is installed in serology lab.

Automated culture system Biomeriuex Bact Alert 3D both for routine pyogenic culture and Mycobacterial culture.

Biomeriuex Vitek 2 System :- Fully computerized identification and susceptibility system for pyogenic bacteria.

Laminar air flow for culture of tubercle bacilli.

Biosafety cabinets for bacterial and fungal culture.

BOD incubator for fungus culture.

Biomeriuex Bact Alert 3D

Biomeriuex Vitek 2 System

Chorus TR10

Biomerieux Minividas

OKAY Laboratory has installed Sysmex XN1000 series six part hematology analyser capable of performing body fluid cell count also.Apart from this we have Sysmex XT2000i(five part hematology analyser), Sysmex CA500 PT Analyser, Diesse vesmatic 20 ESR analyser, Siemens clinitek Advantus/status.

Sysmex CA 500

Sysmex XN 1000

Vesmatic 20

Siemens Clinitek Status

Haemoglobin Electrophoresis and Protein Electrophoresis testing is available on Biorad D 10 and Trivitron-Sebia Minicap Analysers available with us.

Bio-Rad D10

Sebia Mini Cap

OKAY Laboratory has installed Roche Cobas 6000 c system with a capability of performing 1170 test per hour to reduce reporting time and human error. We have installed backup of each instrument to strengthen the delay/failure in reporting.Siemens immulite 2000XPi is installed for triple marker studies.

Roche Cobas 6000

Roche Cobas e411

Roche Cobas c301

OKAY Laboratory has established STAT lab to perform tests for patients in emergency situation with Fujifilm 4000i Dry chemistry analyser.

Fuji DriChem C4000i

Allergy Testing

OKAY Laboratory has installed Phadia 100 & Siemens Immulite 2000 XPi for allergy testing. This is the most accurate and technologically advanced in vitro allergy Testing by blood. Various allergy panels available with us are :-

Dust Panel, Food Panel, Animal Panel, Grass Panel, Inhalant Panel, Tree Panel, Mite Panel, Mold Panel, Weed Panel, other Indian Mixed Panel.

Phadia 100

Siemens Immulite 1000 XPi

OKAY Laboratory has installed Qiagen PCR system with Antibiotic susceptibility testing from Hain’s test.

GenoType MTBDRplus - Your Test System for a Fast and Reliable Way to detect MDR-TB

Identification of the M. tuberculosis complex and its resistance to Rifampicin and/or Isoniazid from pulmonary clinical specimens or cultivated samples

The emergence and spread of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) are a major medical and public problem threatening the global health.

MDR-TB is caused by mycobacteria which are at least resistant to the two most powerful first-line anti-TB drugs rifampicin and isoniazid. Conventional methods for mycobacteria culture and drug susceptibility testing are slow and elaborate, requiring sequential procedures for the diagnosis. During this time patients may be treated inappropriately, drug resistant strains may continue to spread, and amplification of resistance may occur.

Therefore rapid diagnosis and identification of MDR-TB strains are prerequisites for the worldwide fight against TB.

The GenoType MTBDRplus enables a rapid result from pulmonary patient specimen and from culture material. Also for diagnosing patients after treatment failure and relapse, with unknown anamnesis and originating from high prevalence areas of MDR-TB as well as for diagnosing patients in high prevalence TB countries and high burden MDR-TB regions the use ofGenoType MTBDRplus is reasonable. Finally the test can also be applied for screening purposes to develop country-specific TB action plans.

The identification of rifampicin resistance is enabled by the detection of the most significant mutations of the rpoB gene (coding for the β-subunit of the RNA polymerase). For testing the high level isoniazid resistance, the katGgene (coding for the catalase peroxidase) is examined and for testing the low level isoniazid resistance, the promoter region of the inhA gene (coding for the NADH enoyl ACP reductase) is analyzed.

Your benefits with GenoType MTBDRplus

• Can be performed from pulmonary patient specimen and from culture material.
• Results are obtained in 5hrs compared to 1 to 2 months with conventional methods.
• Allows early, appropriate treatment, which reduces transmission and spread of MDR-TB.

Our lab uses this machine for the following tests:

Tuberculosis -Detection of tubercle bacilli detection of resistance gene.

QIA Cube DNA

Real Time PCR

Introduction

Flow cytometry is the measurement of single cells in a fluid suspension. The major benefit of flow cytometers is the capability to rapidly measure and record multiple characteristics of a large number of cells at rates that can exceed 5,000 cells per second, so that even low-frequency cell populations can be quantitated with a high degree of statistical accuracy. Additionally, flow cytometry instrumentation with cell sorting capability provides the ability to recover a selected cell subpopulation in high purity (>95%) from a heterogeneous mixture of cells. The subpopulation can then be used in assays to determine biological function or in other molecular studies.

Flow cytometry has evolved rapidly over the past two decades. The impetus for this advancement was the result of the development of monoclonal antibody technology that allowed the production of large amounts of specific immunological reagents. Today, flow cytometry instrumentation such as the Partec-Sysmex system provides quantitative & qualitative measurement of heterogeneous cell populations based on antigen expression, enzyme activities, and other molecular probes. Consequently, flow cytometry has found broad utility in both cell biology research and in clinical investigations to directly assay immune function, the progression of immunodeficiency diseases such as HIV/AIDS infection, and the diagnosis of recurrence of hematological malignancies. Multipurpose flow cytometer.

The Sysmex –Partec Cube 6 system is another four-color, dual-laser, bench top system available today that is capable of both cell analysis and sorting. Designed specifically to support a wide range of applications, the Sysmex –Partec Cube 6 is a fully integrated multiparameter system.

The Sysmex –Partec Cube 6 system combines unique dual-laser technology, and powerful software to provide the high throughput necessary to meet productivity requirements of clinical laboratories. The modularity and innovative technology designed into the Sysmex –Partec Cube 6 system also offers investigators the performance and flexibility required for a variety of research applications.

The built-in versatility of the Sysmex –Partec Cube 6 flow cytometer meets the current demands of both clinical and research environments. Its flexibility will help you meet tomorrow’s demands.

• Three- or four-color fluorescence capability
• Flexible and modular for future upgrades

Our lab uses this machine for the following tests:

CD3/CD4 / CD8 count.
HLA B-27
Leukemia and lymphoma panels